Peptide APIs

I-MOTS-C

I-MOTS-C API ikhiqizwa ngaphansi kwezimo eziqinile ezifana ne-GMP kusetshenziswa ubuchwepheshe obuqinile besigaba se-peptide synthesis (SPPS) ukuze kuqinisekiswe izinga layo eliphezulu, ukuhlanzeka okuphezulu nokuzinza okuphezulu kocwaningo nokusetshenziswa kokwelapha.
Izici Zomkhiqizo:

Ubumsulwa ≥ 99% (kuqinisekiswe yi-HPLC ne-LC-MS),
I-endotoxin ephansi kanye nokuqukethwe kwe-solvent eyinsalela,
Ikhiqizwe ngokuhambisana ne-ICH Q7 kanye ne-GMP-like protocols,
Ingafinyelela ukukhiqizwa kwezinga elikhulu, kusukela kumaqoqwana e-R&D eleveli ye-milligram ukuya kwezinga legremu kanye neleveli yekhilogremu ukunikezwa kwezohwebo.

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I-Ipamorelin

I-Ipamorelin API ilungiswa nge-high-standard **inqubo ye-peptide synthesis yesigaba esiqinile (SPPS)** futhi ibhekana nokuhlanzwa okuqinile nokuhlolwa kwekhwalithi, okufanelekile ukusetshenziswa kwamapayipi okuqala ocwaningweni lwesayensi nokuthuthukiswa kanye nezinkampani zemithi.
Izici zomkhiqizo zifaka:
Ukuhlanzeka ≥99% (ukuhlolwa kwe-HPLC)
Ayikho i-endotoxin, i-solvent eyinsalela ephansi, ukungcoliswa kwe-ion yensimbi ephansi
Nikeza ngesethi ephelele yamadokhumenti ekhwalithi: I-COA, umbiko wocwaningo lokuzinza, ukuhlaziywa kwe-spectrum yokungcola, njll.
Ukunikezwa kweleveli yegremu ~kilogram-leveli okwenziwa ngokwezifiso

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Pulegone

I-Pulegone i-monoterpene ketone eyenzeka ngokwemvelo etholakala emafutheni abalulekile ezinhlobo ze-mint njenge-pennyroyal, i-spearmint, ne-peppermint. Isetshenziswa njenge-ejenti yesinongo, isakhi samakha, futhi imaphakathi ekuhlanganiseni kwemithi namakhemikhali. I-Pulegone API yethu ikhiqizwa ngezinqubo ezicolisisiwe zokukhipha kanye nokuhlanza ukuze kuqinisekiswe ubumsulwa obuphakeme, ukungaguquguquki, nokuhambisana nezindinganiso ezifanele zokuphepha nekhwalithi.

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I-Etelcalcetide

I-Etelcalcetide iyi-synthetic peptide calcimimetic esetshenziselwa ukwelashwa kwe-hyperparathyroidism yesibili (SHPT) ezigulini ezinesifo sezinso esingamahlalakhona (CKD) ku-hemodialysis. Isebenza ngokuvula i-calcium-sensing receptor (CaSR) kumaseli e-parathyroid, ngaleyo ndlela yehlise amazinga e-parathyroid hormone (PTH) futhi ithuthukise umzimba wamaminerali. I-high-purity Etelcalcetide API yethu ikhiqizwa nge-solid-phase peptide synthesis (SPPS) ngaphansi kwezimo ezithobela i-GMP, ezifanele ukwakheka komjovo.

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I-Bremelanotide

I-Bremelanotide iyi-peptide yokwenziwa kanye ne-melanocortin receptor agonist eyenzelwe ukwelashwa kwe-hypoactive sex passion disorder (HSDD) kwabesifazane abangaphambi kokuya esikhathini. Isebenza ngokuvula i-MC4R ohlelweni lwezinzwa olumaphakathi ukuthuthukisa isifiso socansi nokuvusa inkanuko. I-high-purity API yethu ye-Bremelanotide ikhiqizwa nge-solid-phase peptide synthesis (SPPS) ngaphansi kwamazinga aqinile ekhwalithi, afanele ukwakheka komjovo.

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I-Etelcalcetide Hydrochloride

I-Etelcalcetide Hydrochloride iyi-ejenti yokwenziwa ye-peptide-based calcimimetic esetshenziselwa ukwelapha i-hyperparathyroidism yesibili (SHPT) ezigulini ezinesifo sezinso esingamahlalakhona (CKD) ku-hemodialysis. Isebenza ngokuvula i-calcium-sensing receptors (CaSR) ku-parathyroid gland, ngaleyo ndlela yehlise amazinga e-parathyroid hormone (PTH) futhi ithuthukise ibhalansi ye-calcium-phosphate. I-Etelcalcetide API yethu ikhiqizwa nge-high-purity peptide synthesis futhi ithobelana nezindinganiso zamazwe ngamazwe zemikhiqizo ejovayo yezinga lezemithi.

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I-Desmopressin Acetate Ukwelapha i-Diabetes Insipidus ephakathi

Igama: Desmopressin

Inombolo ye-CAS: 16679-58-6

Ifomula yemolekyuli: C46H64N14O12S2

Isisindo se-molecule: 1069.22

Inombolo ye-EINECS: 240-726-7

Ukujikeleza okuqondile: D25 +85.5 ± 2° (kubalwe i-peptide yamahhala)

Ukuminyana: 1.56±0.1 g/cm3(Kubikezelwe)

Inombolo ye-RTECS: YW9000000

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I-Eptifibatide yokwelashwa kwe-Acute Coronary Syndrome 188627-80-7

Igama: Eptifibatide

Inombolo ye-CAS: 188627-80-7

Ifomula yemolekyuli: C35H49N11O9S2

Isisindo se-molecule: 831.96

Inombolo ye-EINECS: 641-366-7

Ukuminyana: 1.60±0.1 g/cm3(Kubikezelwe)

Izimo zokugcina: Kuvalwe endaweni eyomile, gcina efrijini, ngaphansi kuka -15°C

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I-Terlipressin Acetate Yokopha Kwe-Esophageal Variceal

Igama: N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin

Inombolo ye-CAS: 14636-12-5

Ifomula yemolekyuli: C52H74N16O15S2

Isisindo se-molecule: 1227.37

Inombolo ye-EINECS: 238-680-8

Indawo yokubilisa: 1824.0±65.0 °C (Kubikezelwe)

Ukuminyana: 1.46±0.1 g/cm3(Kubikezelwe)

Izimo zesitoreji: Gcina endaweni emnyama, emkhathini ongenamoya, Gcina efrijini, ngaphansi kuka -15°C.

I-acidity coefficient: (pKa) 9.90±0.15 (Kubikezelwe)

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I-Teriparatide Acetate API ye-Osteoporosis CAS NO.52232-67-4

I-Teriparatide iyi-synthetic 34-peptide, i-1-34 amino acid fragment ye-hormone ye-parathyroid ye-PTH, okuyindawo esebenzayo ye-N-terminal ye-84 amino acid endogenous parathyroid hormone PTH. Izici ze-immunology kanye ne-biological zalo mkhiqizo zifana ncamashi nalezo ze-hormone ye-parathyroid engapheli i-PTH kanye ne-hormone ye-bovine parathyroid PTH (bPTH).

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I-Atosiban Acetate Isetshenziselwa Ukuzalwa Okungakabi Isikhathi

Igama: Atosiban

Inombolo ye-CAS: 90779-69-4

Ifomula yemolekyuli: C43H67N11O12S2

Isisindo se-molecule: 994.19

Inombolo ye-EINECS: 806-815-5

Indawo yokubilisa: 1469.0±65.0 °C (Kubikezelwe)

Ukuminyana: 1.254±0.06 g/cm3(Kubikezelwe)

Izimo zokugcina: -20°C

Ukunyibilika: H2O: ≤100 mg/mL

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I-Carbetocin Yokuvimbela Ukufinyela Kwesibeletho kanye Nokopha Kwangemva Kokubeletha

Igama: CARBETOCIN

Inombolo ye-CAS: 37025-55-1

Ifomula yemolekyuli: C45H69N11O12S

Isisindo se-molecule: 988.17

Inombolo ye-EINECS: 253-312-6

Ukujikeleza okuqondile: D -69.0° (c = 0.25 ku-1M acetic acid)

Indawo yokubilisa: 1477.9±65.0 °C (Kubikezelwe)

Ukuminyana: 1.218±0.06 g/cm3(Kubikezelwe)

Izimo zokugcina: -15°C

Ifomu: powder

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