Atosiban Acetate Used for Anti Premature Birth Featured Image

I-Atosiban Acetate Isetshenziselwa Ukuzalwa Okungakabi Isikhathi

Incazelo emfushane:

Igama: Atosiban

Inombolo ye-CAS: 90779-69-4

Ifomula yemolekyuli: C43H67N11O12S2

Isisindo se-molecule: 994.19

Inombolo ye-EINECS: 806-815-5

Indawo yokubilisa: 1469.0±65.0 °C (Kubikezelwe)

Ukuminyana: 1.254±0.06 g/cm3(Kubikezelwe)

Izimo zokugcina: -20°C

Ukunyibilika: H2O: ≤100 mg/mL

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Imininingwane Yomkhiqizo

Igama	Atosiban
Inombolo ye-CAS	90779-69-4
Ifomula yamangqamuzana	I-C43H67N11O12S2
Isisindo samangqamuzana	994.19
Inombolo ye-EINECS	806-815-5
Iphuzu elibilayo	1469.0±65.0 °C (Kubikezelwe)
Ukuminyana	1.254±0.06 g/cm3(Kubikezelwe)
Izimo zokugcina	-20°C
Ukuncibilika	I-H2O:≤100 mg/mL

Incazelo

I-Atosiban acetate iyi-polypeptide eyi-disulfide-bonded cyclic ehlanganisa ama-amino acid ayi-9.Kuyi-molecule ye-oxytocin eguquliwe ezindaweni 1, 2, 4 kanye no-8. I-N-terminus ye-peptide yi-3-mercaptopropionic acid (thiol kanye neqembu le-sulfhydryl le- [Cys] 6 lakha ibhondi ye-disulfide), i-C-terminal ngesimo se-amide, i-amino acid yesibili ku-N-terminal iyi-ethylated modified [D-Tyr(Et)]2, futhi i-atosiban acetate isetshenziswa emithini njengoviniga Ikhona ngesimo sikasawoti we-asidi, ngokuvamile. eyaziwa ngokuthi i-atosiban acetate.

Isicelo

I-Atosiban iyi-oxytocin kanye ne-vasopressin V1A ehlanganisiwe ye-receptor antagonist, i-oxytocin receptor ifana nesakhiwo se-vasopressin V1A receptor.Uma i-oxytocin receptor ivinjiwe, i-oxytocin isengakwazi ukusebenza ngesamukeli se-V1A, ngakho-ke kuyadingeka ukuvimba izindlela ezimbili zama-receptor ezingenhla ngesikhathi esisodwa, futhi ukuphikiswa okukodwa kwesamukeli esisodwa kunganqanda ngempumelelo ukufinyela kwesibeletho.Lesi futhi esinye sezizathu eziyinhloko zokuthi kungani ama-β-receptor agonists, i-calcium channel blockers kanye ne-prostaglandin synthase inhibitors engakwazi ukuvimbela ngokuphumelelayo ukufinyela kwesibeletho.

Umphumela

I-Atosiban iyinhlangano ehlangene ye-receptor antagonist ye-oxytocin ne-vasopressin V1A, ukwakheka kwayo kwamakhemikhali kufana nalokhu okubili, futhi inobudlelwane obuphezulu be-receptors, futhi iqhudelana ne-oxytocin ne-vasopressin V1A receptors, ngaleyo ndlela ivimbe indlela yesenzo se-oxytocin ne-vasopressin nokunciphisa. ukufinyela kwesibeletho.

Okwedlule: I-Teriparatide Acetate API ye-Osteoporosis CAS NO.52232-67-4

Olandelayo: I-Carbetocin Yokuvimbela Ukufinyela Kwesibeletho kanye Nokopha Kwangemva Kokubeletha

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