I-Desmopressin acetate ukwelapha i-central sikashukela insipidus
Imininingwane Yomkhiqizo
| Ibizo | I-Desmopressin |
| Inombolo ye-CAS | 16679-58-6 |
| Ifomula yamangqamuzana | C46h64n14o12s2 |
| Isisindo molecular | I-1069.22 |
| Inombolo ye-einec | 240-726-7 |
| Ukujikeleza okuthile | I-D25 +85.5 ± 2 2 ° (kubalwa i-peptide yamahhala) |
| Incekusana | 1.56 ± 0.1 g / cm3 (abikezelwe) |
| Rtec No. | Yw9000000 |
| Izimo Zokugcina | Gcina ku-0 ° C |
| Ubuhlakaniselo | I-H2O: Soluble20MG / ML, Sula, Ungenamibala |
| I-acidity coccifflity | (PKA) 9.90 ± 0.15 (Ebikezelwe) |
Amanyanjana
I-MPR-TRY-PRE-PHE-GLN-ASN-CYS-Pro-D-Gly-NH2; Minirin; [I-DARGONI1, DARG8] Vasopressin; [I-Deamino-CYS1, D-ARG8] -Vasopressin; DDAVP, Omuntu; Desmopressin; Desmopressin, umuntu; I-Desamono- [d-aggn8] Vasopressin
Izinkomba
(1) Ukwelashwa kwesifo sikashukela esiseCentral Insiphidus. Ngemuva kokuthi umuthi unganciphisa ukukhishwa kwe-urinary, wehlisa imvamisa ye-urinary futhi wehlise i-nocturia.
(2) Ukwelashwa kwe-Nocturnal Ensures (iziguli ezineminyaka engu-5 ubudala noma ngaphezulu).
(3) Hlola umsebenzi wokuhlushwa kwe-renal umchamo, bese wenza ukuxilongwa okuhlukile komsebenzi we-renal.
(4) ye-hemophilia nezinye izifo zokopha, lo mkhiqizo unganciphisa isikhathi sokusopha futhi uvikele ukopha. Kunganciphisa inani lokulahleka kwegazi elisebenzisana ne-intraperative ne-oosing postoperative; Ikakhulu ngokuhlangana nomfutho wegazi olawulwa ngokufanelekile ngesikhathi sokuhlinzwa, kunganciphisa ukopha okungabambisane kusuka ezindleleni ezahlukahlukene, futhi kunciphise i-postictive Oozing, engadlala indima engcono ekuvikelweni kwegazi.
Ukwelashwa kwesifo sikashukela insiptus
Isifo sikashukela Insiphidus ngokuyinhloko ukuphazamiseka kwe-metabolism yamanzi ebonakala ngokukhipha umchamo owedlulele, i-polydipsipsia, i-hypoosmololia, ne-hyperremia. Ukuntuleka okuyingxenye noma okuphelele kwe-Vasopressin (Central Diabetes Insiphidus), noma ukuphefumula kwe-renal of vasopression (i-Nephrogenic Diabetes Insiphidus) kungaqala. Ngokwenyama, isifo sikashukela i-instipidus siyafana ne-polydipsisia eyinhloko, isimo lapho ukudliwa kwamanzi ngokweqile kubangelwa ukungasebenzi kahle kwendlela yokulawula noma ukoma okungajwayelekile. Ngokuphikisana ne-polydipsia eyinhloko, ukwanda kokuthathwa kwamanzi ezigulini ezinesifo sikashukela i-insipidus kuyinto ehambelana nempendulo ehambelana nengcindezi ye-osmotic noma ivolumu yegazi.
