I-Teriparatide Acetate API ye-Osteoporosis Case No.52232-67-4

Incazelo emfushane:

I-Teriparatide iyi-peptide yokwenziwa engu-34, i-amino acid Fragment ye-Human Parathyroid Hormone Pth, okuyisifunda esisebenzayo se-N-terminal of the 8 ama-amino acid ama-acid e-endogenous Parmone Pth. Izakhiwo ze-Immunological and Biological zalo mkhiqizo zifana ncamashi nalezo ze-endossous parathyroid Hormone Pth kanye ne-Bovine Parathyroid Hormone Pth (BPTH).

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Amathegi Omkhiqizo

Imininingwane Yomkhiqizo

Ibizo	I-Teriparatide Acetate
Case No.	52232-67-4moletular
Uhlobo	C181H291N55O51S2
Ukubonakala	mhlophe ukuvala okumhlophe
Isikhathi sokuthumela	Isilungele esitokweni
Isishuqulu	I-Aluminium Foil Bag
Ubumsulwa	≥98%
Ukubeka	2-8 degree
Ukuthutha	Iketanga elibandayo nokulethwa okupholile kokugcina

Amanyanjana

Parathyroidhormorehuman: 20-34; Parathyroidhormone (umuntu, 1-34); Parathyroidhormone (1-34), umuntu; Pth (1-34) (umuntu); Pth (umuntu, 1-34); Teraparatide; I-teriparatide acetate.

Sebenza

I-Teraparatide ingahle ilimise i-metabolism yethambo ngokuvimbela i-osteoblast apoptosis, isebenze amaseli okulahla ithambo, kanye nokwenza ngcono umehluko we-osteoblast. I-Intandly ivuselela i-Pht-I Receptor ebusweni be-Osteoblasts, amangqamuzana e-Bone Linting kanye nama-Bone Marrow Stromal Stem Amaseli ngokulawula i-Adenylate Cyclase-Amaprotheni Kuvuselela ukwanda kwemigqa ye-osteoblast cell calcium c-cytoplasmic chercium-protein chemicbook Kinase C Signaling Path; Ngokuvimbela umsebenzi we-transacctivation we-phparxwa, kunciphisa umehluko wamaseli asemqhele e-Adipocyte Lineage futhi kwandise inani lama-osteoblasts; Ukulawula ngokungaqondile ukukhula kwamathambo ngokulawula ama-cytokines, ngokwesibonelo, i-IGF-1 ingadonswa ukubopha ama-osteoblasts, ngaleyo ndlela kukhuthaze ukwakheka kwamathambo;

Inqubo yokwakheka kwamathambo ilawulwa yi-WNT Signaling Patway, ngaleyo ndlela yanda ukwakheka kwamathambo.

Umthandi

Ungakwazi yini ukunikeza imibhalo efanele?

Yebo, singanikeza amadokhumenti amaningi kubandakanya nezitifiketi zokuhlaziywa / ukuvumelana; Umshuwalense; Imvelaphi, kanye neminye imibhalo yokuthumela lapho kudingeka khona.

Uhlelo lwekhwalithi

Ngokuvamile, uhlelo lwekhwalithi kanye nesiqinisekiso selusendaweni ehlanganisa lonke isigaba sokukhiqizwa komkhiqizo ophelile. Ukusebenza okwanele nokulawula ukusebenza kwenziwa ngokuhambisana nezinqubo / imininingwane evunyelwe. Ukushintsha kolawulo kanye nokuphambuka kohlelo kusendaweni, futhi kwenziwa ukuhlolwa komthelela kanye nophenyo. Izinqubo ezifanele zisendaweni yokuqinisekisa ikhwalithi yomkhiqizo ngaphambi kokuyikhipha emakethe.

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