IVancomycin iyi-antibiotic esetshenziselwa i-antibacterial
Imininingwane Yomkhiqizo
| Ibizo | Vancomycin |
| Inombolo ye-CAS | 1404-90-6 |
| Ifomula yamangqamuzana | C66h75ccl2n9o24 |
| Isisindo molecular | 1449.25 |
| Inombolo ye-einec | 215-772-6 |
| Incekusana | 1.2882 (isilinganiso esinzima) |
| Inkomba ye-Refuac | 1.7350 (ukulinganisa) |
| Izimo Zokugcina | Kuvalwe e-Dry, 2-8 ° C |
Amanyanjana
I-Vancomycin (baseAseAnd / Orunspeciedsalts); Vancomycin; Vancomycinbase; (3s, 6r, 7r, 36r, 28: 28: 28I-28: 3,6-Tridexy-3-C-HTYL-α-Lyxo-Hexocyranosyl) I-Oxy] -10-D-Dichloro-2,3,3,5,6,7,3,3,3,6,8,38,37,38A-TETRADECHA-7 , 22,28,30,32-PentaHyDroxy-6 - [[(2r) -4-MethtechemicalBookBookBookBookyl-2- (methyalino) -1-25 36- (Iminomethano) -13,16: 31,16-Dimetheno-1h, 16,6,9] I-Benzoxacyclohetracosino [3,6,6,9] I-Benzoxasiazacyclotetracosine-26-carboxylicacid.
Ukufanisa
I-Vancomycin iyi-antibiotic ethinta i-glycopeptide. Indlela yayo yesenzo ukubopha nge-afferalinity ephezulu kuya e-Alanyalanine endaweni yokuphelelwa yi-poly-terminal yodonga lwe-macromolecular cell, okuholele ekubhujisweni kodonga lwensimbi kubulala amagciwane. IVancomycin iyasebenza ekuthelelekeni okungathithi abangelwa amagciwane ane-gram-positive, ikakhulukazi labo abangelwa i-staphylococcus are areus, ne-entephylococcus epidermidis, kanye ne-enterococcus emelana namanye ama-antibiotics noma asebenze kahle.
Izinkomba
Kukhawulelwe ekuthelelekeni okuhleliwe okubangelwa i-methicillin-starphylococcus aureus (MRSA) kanye nokutheleleka kwamathumbu kanye nezifo ezihleliwe ezibangelwa yi-Closeridium Effile; Iziguli ze-penicillin-allergic azikwazi ukusebenzisa i-penicillins noma ama-cephalosporins ezigulini ezinokutheleleka okukhulu kwe-staphylococcal, noma lezo ezinokutheleleka okukhulu kwe-staphylococcal ahlulekile ukuphendula kule mishanguzo engenhla, i-vancomycin ingasetshenziswa. Lo mkhiqizo ubuye usetshenziselwe ukwelashwa kwe-Enterococcus endocarditis kanye ne-corynebacterium (diphtheria-like) endocarditis kubantu abangahambi kahle kwi-penicillin. Ukwelashwa kwezifo ze-staphylococcus-ezibangelwe izifo ze-arteriovenous shunt ezigulini ze-heodialysis Alergic kuya ePhenicillin ne-non-adlergic ePhenicillin.
