I-Vancomycin iyi-antibiotic ye-glycopeptide esetshenziselwa i-antibacterial
Imininingwane Yomkhiqizo
| Igama | I-Vancomycin |
| Inombolo ye-CAS | 1404-90-6 |
| Ifomula yamangqamuzana | I-C66H75Cl2N9O24 |
| Isisindo samangqamuzana | 1449.25 |
| Inombolo ye-EINECS | 215-772-6 |
| Ukuminyana | 1.2882 (isilinganiso esinzima) |
| Inkomba ye-refractive | 1.7350 (isilinganiso) |
| Izimo zokugcina | Ivalwe endaweni eyomile, 2-8°C |
Omqondofana
Vancomycin(usawoti oyisisekelo kanye/orunspecified);VANCOMYCIN;VancomycinBase;(3S,6R,7R,22R,23S,26S,36R,38aR)-3-(2-Amino-2-oxoethyl)-44-[[2-O-(3-amino-2, 3,6-trideoxy-3-C-methyl-α-L-lyxo-hexopyranosyl)-β-D-glucopyranosyl]oxy] -10,19-dichloro-2,3,4,5,6,7,23,24,25,26,36,37,38,38a-7a-7 ,22,28,30,32-pentahydroxy-6-[[(2R)-4-methChemicalbookyl-2-(methylamino)-1-oxopentyl]amino]-2,5,24,38,39-pentaoxo-22H-8,11:18,21-Dietheno-23, 36-(iminomethano)-13,16:31,35-dimetheno-1H,16H-[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylicacid.
Incazelo
I-Vancomycin iyi-antibiotic ye-glycopeptide. Indlela yayo yokusebenza iwukubopha ngokusondelana okuphezulu ne-alanylalanine ekugcineni kwe-poly-terminal ye-peptide eyandulela yodonga lweseli yebhaktheriya ebucayi, kuvinjwe ukuhlanganiswa kwe-macromolecular peptidoglycan eyakha udonga lweseli yebhaktheriya, okuholela ekubhujisweni kodonga lweseli kubulala amagciwane. I-Vancomycin iyasebenza ezifweni ezimbi kakhulu ezibangelwa amagciwane e-Gram-positive, ikakhulukazi lawo abangelwa i-Staphylococcus aureus emelana ne-methicillin, i-Staphylococcus epidermidis, ne-Enterococcus engazweli kwamanye ama-antibiotic noma angasebenzi kahle.
Izinkomba
Kunqunyelwe ezifweni zesistimu ezibangelwa i-Staphylococcus aureus (MRSA) engamelana ne-methicillin (MRSA) kanye nezifo zamathumbu kanye nezifo zesistimu ezibangelwa i-Clostridium difficile; iziguli ze-penicillin-allergic azikwazi ukusebenzisa i-penicillin noma i-cephalosporins ezigulini ezinokutheleleka okunzima kwe-staphylococcal, noma lezo ezinokutheleleka okukhulu kwe-staphylococcal ezihlulekile ukusabela kulawa ma-antibiotic angenhla, i-vancomycin ingasetshenziswa. Lo mkhiqizo usetshenziselwa ukwelapha i-Enterococcus endocarditis kanye ne-Corynebacterium (i-Diphtheria-like) endocarditis kubantu abangazwani ne-penicillin. Ukwelashwa kwe-staphylococcus-induced arteriovenous shunt infections ezigulini ze-hemodialysis ezingezwani ne-penicillin kanye ne-non-allergic to penicillin.
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