I-Sildenafil Citrate ukuphatha i-erectile dysfunction 171599-83-0

Incazelo emfushane:

Ifomula yamakhemikhali: C28h38N6O11S

Isisindo Molecular: 666.70

Inombolo ye-CAS: 171599-83-0

Inombolo ye-EINECS: 200-659-6

Iphoyinti Lokuncibilika: 187-189 ℃

Iphuzu elibilayo: 672.4 ℃

I-Flash Point: 360.5 ℃

Ubuningi: 1.445G / CM3

I-Index Resuactive: 1.683

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Amathegi Omkhiqizo

Imininingwane Yomkhiqizo

Ibizo	I-sildenafil citrate
Inombolo ye-CAS	171599-83-0
Ifomula yamangqamuzana	C28H38N6O11S
Isisindo molecular	I-666.70
Inombolo ye-einec	200-659-6
I-Merck	14,8489
Incekusana	1.445G / CM3
Isimo sokugcina	2-8 ° C
Isithunzi	Impushana
Umbala	Okumhlophe
I-solubity yamanzi	DMSO:> 20mg / ml

Amanyanjana

I-Viagra, i-Sildenafil CITRATION; 1 - [[3- 4,7-Dihydro-1-methy-7-oxe-prepl-1h-pyrazolo [4,3-d] Pyrimidin-5-yl) -4-ethoxyfani] -4-ethoxyphenyl] Sulfonyl] -4-thykyylyl] -4-jyams] 5- [2-Ephoxy-5- (4-ylyliperazin-1-yl) sulfonyphenyl] -1-methyl-3-propl-4h-phyrazolo [5,4-e] Pyrimidin-7-onecitrateAlt; 1 - [[3-7- (6-2,7-Dihydro-1-Methto-3-Prepl-1h-Pyrazolo [1,3-D] Pyrimidin-5-yl) -4-eMoxyphenyl] Sulfonyl] - 4 I-Sildenafilcitte (100mg); I-sildenafilcittirate,> = 99%; Sildenafilcitrate, ochwepheshe; 5- 2-Ephoxy-5 - [(4-methyl-piperazin-1-yl) sulfonyl] Phenyl] Phenyl] -1,6-Dihydro-1-I-Methyl-3-PPRYL-3-PPYL-7H-PIRYL-7H-PIRYL-7H-PIYIMIDIN-7

Umphumela wekhemisi

Isenzo samakhemisi
I-Sildenafil CITRERAT yi-inhibitor ekhethiwe engu-5-phosphodiesterase ethuthukisa i-nitric oxide-encike ye-pulmonary Vasodilation ngokuvimbela ukwephulwa kwe-monosphate ye-cyclic Guanosine. Ngaphezu kokunwetshwa okuqondile kwemithambo yegazi ye-pulmonary, kungavimbela futhi noma ukubuyisela kabusha ukulungisa kabusha kwe-vascular.

Izakhiwo zokwelapha kanye nezinhlelo zokusebenza
I-Sildenafil CITRATE, Igama Lokuhweba I-Viagra, elaziwa ngokuthi i-Viagra, yi-Cyclic Guanosine Monophosphate (CGMP) -Specific PhosphoDeesserase 5 (PDE5) inhibitor engathuthukisa ukwakheka ngemuva kokuphathwa komlomo. I-Sildenafil Curtrate ingathuthukisa umphumela we-nitric oxide (cha) ngokuvimbela uhlobo lwe-5 phosphodererase olubola nge-cyclic Guanosine Monophosphate (CGMP) eCorpus Casernosum. Khuphula izinga le-CGMP ku-Corpus Casernosum, phumula umsipha obushelelezi e-Corpus Casernosum, ukhuphule ukungena kwegazi, unwebise isikhathi sokwenziwa penis futhi wandise ukuqina. Iziguli ezingekho emthethweni ezinokungasebenzi kahle kwe-erectile. Abantu abadala bathatha i-50 mg ngomlomo isikhathi ngasinye, kuze kube yisikhathi esingu-1 ngosuku, futhi bayisebenzise njengoba kudingeka cishe ngehora eli-1 ngaphambi kokuya ocansini. Inani eliphakeme lingu-0.1G isikhathi ngasinye.

Ezifundweni ze-Vivo
Ezinjeni ezinobuntu, i-Sildenafil Citrate kuthuthukisa umsebenzi we-penile erectile umsebenzi ngaphansi kokukhuthaza kwezinzwa ze-pelvic ngokulinganisa ingcindezi ye-intracavernous. I-Sildenafil CITRERELWE NGOKUGCWELEKILE KAKHULU KAKHULU KAKHULU KAKHULU KAKHULU KAKHULU KANYE NOKUXHUMANISA I-Huleroxide Discuration eziculweni zeCavernosal of Hypercholesterolemic Obbicile. ESprague-Dawley Rats, i-Sildenafil ithuthukisa umsebenzi we-erectile ngendlela ethembele yethamo lesikhathi, ngokubuyiselwa kwemali okuphezulu okwenzeka ngosuku lwe-28 ngethamo le-20 mg / kg ngosuku. ESprague-Dawley Rats, ukuphathwa kwe-Sildenafil kuholele ekugcinweni kwesilinganiso se-Smooth Muscle Collagen Collagen kanye nokulondolozwa kwe-CD31 ne-Enos Express. ESprague-Dawley Rats, i-Sildenafil inciphise kakhulu inkomba ye-apoptotic futhi yandisa i-phosphorylation ye-Akt ne-Enos ngokuqhathaniswa neqembu elilawulayo.

Okwedlule: I-Tadalafil 171596-29-5 ukwelapha ukungasebenzi kwe-erectile emadodeni

Olandelayo: I-Vardenafil Dihydrochloride Ukuphatha I-Erectile Dysfuction 224785-91-5

Bhala umyalezo wakho lapha bese usithumela kithi