Ru-58841 Kusetshenziswe Njengokuvimbela Ukulahleka Kwezinwele kanye Nemaphethini Yesilisa

Ukufanisa

Ru 58841 (PSK-3841) ingumphikisi we-androgen receptor okhuthaza ama-hair regrowth.I-Ru58841 iyisidakamizwa sokuphenya esenzelwe ukwelashwa nge-angopecia ye-androgenic, eyaziwa nangokuthi impandla yephethini yabesilisa (MPD).

Njengo-antical anti-androgen oyisisekelo, umgomo wawo owenziwayo akafani naleso sokuqala. I-Finasteresteaterestereste isebenza nge-5α reurcase, ivimbela ukuguqulwa kwe-testosterone ku-DHT, futhi kunciphise okuqukethwe kwe-DHT emzimbeni. I-Ru58841 ivimba oxhumana naye phakathi kwe-dihydrotestorenorene kanye nezinwele ama-receptoresteresterone ne-follicle, akunciphisi ngokuqondile okuqukethwe kwe-DHT, kepha kunciphisa ukubopha ama-DHT nama-follicle wezinwele, ukuze kufinyelelwe inhloso yokwelapha i-alopecia ye-androgenetic.

4- [3- (4-HydroxyButyl) -4,4-Dimethyl-2,5-Dioxo-1,5-IMidazolidinyl] -2-Imidazolididinyl] -2- (Trifluoromethyl) IBenzinitrile ingasetshenziswa njenge-Medicine Chemical syntheris syntheris.Uma 4- [3-HydroxyButyl) -4,4-Dimethyl-2,5-dioxo-1,5-midazolidinyl] -2- (trifluoromethyl) iBenzonitrile ihanjiswa, hambisa isiguli emoyeni omusha;Uma uthintana nesikhumba, ususe izingubo ezingcolile, geza isikhumba ngensipho nangamanzi, futhi ufune usizo lwezokwelashwa uma kungenjalo ukungaphatheki kahle;

Umphumela wecala

I-RU58841 isetshenziswa esihlahleni, edonswe yizinwele zama-follicle, futhi ngokweqiniso, ingangena egazini futhi ithinta ezinye izingxenye zomzimba. Kepha akukho miphumela emibi ehleliwe etholwe ezifundweni zohlelo lokusebenza lwezinkawu ezinhlamvu. Kodwa-ke, abanye abantu abake bazama ru58841 bafuna ukuthi bathole imiphumela emibi engenzeka ekusebenziseni i-ru, kufaka phakathi ukucasuka kwesikhumba, kuncishiswe i-libido, isicanucanu se-erectile, isicanucanu, nekhanda.