Paclitaxel 33069-62-4 Anti-Tumor Botanical Medicine for Cancerian Cancer, Cancernce Cancer

Ukufanisa

I-PacliTaxel yi-monomeric diterpenoid ekhishwe kusuka kumagxolo e-Natural Trap Tables Medicine. I-Isotope Traceng ikhombisile ukuthi i-paclitaxel iboshelwe kuphela kuma-polymerized microtubule futhi ayizange iphendule ngemiphetho ye-tubulin engavunyelwe. Ngemuva kokuthi amaseli avezwe ku-paclitaxel, kuzoqongelelwa inani elikhulu le-microtubule kumaseli. Ukuqongelelwa kwalawa ma-microtubule kuphazamisa imisebenzi ehlukahlukene yamaseli, ikakhulukazi ukwahlukaniswa kwamaseli kuyeka esigabeni se-mitotic futhi kuvimba ukwahlukaniswa okujwayelekile kwamaseli. Ngokusebenzisa ucwaningo lwe-ⅱ-ⅲ, i-paclitaxel ilungele kakhulu umdlavuza we-ovarian nomdlavuza webele, futhi inomdlavuza othile olapha emdlavuza wamaphaphu, umdlavuza we-coloul, melanoma, umdlavuza wentamo, i-lymphoma kanye nomdlavuza wobuchopho.

Izinkomba

Inomphumela omuhle ekwelashweni komdlavuza we-ovarian kanye neplatinamu nomdlavuza we-avarian wokuphambuka kanye nomdlavuza webele. Umdlavuza, umdlavuza wesisu ophezulu, iseli elincane nomdlavuza weseli ongewona omncane unesimo esihle.

Sisebenzise

Sebenzisa i-1: Broad-spectrum anti-tlans botanicals yomdlavuza we-ovarian, umdlavuza webele, njll.

Sebenzisa 2: Broad-Spectrum anti-Tumecrum anti-Tumula botanicals yokwelashwa komdlavuza we-ovari, umdlavuza webele nezinye izifo.

Sebenzisa 3: Izidakamizwa ze-Antitumor. Ukwelashwa komdlavuza webele we-metastatic kanye nomdlavuza we-ovarian we-metastatic. I-Broad-Spectrum Anti-Tumor Botanicals yokwelashwa komdlavuza we-ovarian, umdlavuza webele nezinye izifo.

Sebenzisa 4: umuthi ophumelelayo wokulwa nomthetho; Ibopha esifundeni se-n-terminal se-β-tubulin, ikhuthaza amafomethi aqinile ama-microtubule, imelana ne-depolymerization, ivimbela ukuhlukaniswa kwamaseli okujwayelekile kanye nezicupho esigabeni se-G2 / m somjikelezo weseli.

Sebenzisa i-5: Isidakamizwa esilwa ne-microtuvule, kuvimbela ukudonswa kwe-depolymerization ngokuqhakambisa i-tubulin polymerization, ukulondolozela ukuqina kwe-tubulin, nokuvimbela i-mitosis cell.