Orlistat 96829-58-5 Ukunciphisa ukumuncwa kwamafutha wesitaya, okuholela ekulahlekelweni kwesisindo

Izakhiwo

I-White Crystalline Powder, icishe ibe insoluble emanzini, incibilike kalula ku-chloroform, inyumbazane ngokweqile e-methanol nase-ethanol, kulula ukuya e-pyroly, iphuzu elincibilikayo, i-callting point ingu-40 ℃ ~ 42 ℃. I-molecule yayo i-diatereomer equkethe izikhungo ezine ze-chiral, endaweni yakwa-5299, isixazululo sayo se-ethanol inokujikeleza okungalungile.

Imodi Yesenzo

I-Orlistat ingu-gastrointestinalinalinalinalinalitinal enamandla we-liptrointestinalinalinalinalinalinalinalinalinalinalinal Ama-enzymes angasebenzi angeke ahlukanise amanoni ekudleni kuma-acid ama-fatty acid kanye namakhemikhali Glycerol angadonswa ngumzimba, ngaleyo ndlela anciphise ukudla kwamafutha nokunciphisa isisindo. Ngaphezu kwalokho, ezinye izifundo zithole ukuthi i-Orlistat ivimbela ukumuncwa kwamathumbu kwe-cholesterol ngokuvimbela amaprotheni we-niemann-pick C1

Izinkomba

Lo mkhiqizo ngokuhlanganiswa nokudla kwe-hypocallaloric emnene kukhonjiswa ukwelashwa kwesikhathi eside kwabanye abantu abaningi abakhuluphele ngokweqile, kubandakanya nalabo abanezinto ezisengozini ezihlanganisiwe ezihambisana nokukhuluphala. Lo mkhiqizo unokulawulwa kwesisindo isikhathi eside (ukunciphisa isisindo, ukulungiswa kwesisindo nokuvimbela ukuphindisela) ukusebenza. Ukuthatha i-Orlistat kunganciphisa izici zobungozi ezihlobene nokukhuluphala kanye nezehlakalo zezifo ezihlobene nokukhuluphala, kufaka phakathi isifo sikashukela esingu-2, ukubekezelela i-glucose, i-hypertensinemia, i-hypertension, kanye nokuqukethwe kwamafutha okunciphisa.

Ukusebenzisana Kwezokwelapha

Kunganciphisa ukumuncwa kwamavithamini A, D no-E. Kungangezelelwa ngalo mkhiqizo ngasikhathi sinye. Uma uthatha amalungiselelo aqukethe amavithamini a, d no-E (njengamanye ama-multivitamins), kufanele uthathe lo mkhiqizo amahora ama-2 ngemuva kokuthatha lo mkhiqizo noma ngasikhathi sokulala. Abantu abanesifo sikashukela sohlobo 2 bangadinga ukunciphisa umthamo wama-oral hypoglycemic agents (isib., SulfonyLureas). Ukuphathwa ngokubambisana nge-cyclosporine kungaholela ekunciphiseni ekugxileni kokugcina kwe-plasma. Ukusetshenziswa okuhlangene kwe-Amoodarone kungahle kube nomphumela wokuncishiswa kokugcina nokuncishiswa kwempumelelo.