I-Motixafortide

I-Motixafortide API

I-Motixafortide iyi-peptide yokwenziwa ye-CXCR4 ephikisanayo eyenzelwe ukuhlanganisa amangqamuzana e-hematopoietic stem (HSCs) ukuze kufakwe i-autologous transplantation futhi iyacwaningwa ku-oncology kanye ne-immunotherapy.

Inqubo Nocwaningo:

I-Motixafortide ivimba i-axis ye-CXCR4-SDF-1, okuholela ku-:
Ukuhlanganisa i-stem cell ngokushesha egazini le-peripheral
Ukushushumbiswa kwamaseli omzimba okuthuthukisiwe kanye nokungena kwesimila
I-synergy engaba khona ngama-checkpoint inhibitors kanye ne-chemotherapy

Ibonise isivuno esiphezulu se-stem cell uma kuqhathaniswa nabagqugquzeli abakhona ezivivinyweni zomtholampilo.
Izici ze-API (Gentolex Group):

I-peptide yokwenziwa ehlanzekile ephezulu
Amazinga okukhiqiza afana ne-GMP
Ifanele ukwakheka komjovo

I-Motixafortide API isekela ucwaningo oluthuthukisiwe ekwelashweni kwe-stem cell kanye ne-immunotherapy yomdlavuza.