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I-MicAFungin ye-antifungal ne-antiviral

Incazelo emfushane:

Igama: MicAfungin

Inombolo ye-CAS: 235114-32-6

Ifomula yamangqamuzana: c56h71N9o23s

Isisindo se-Molecular: 1270.28

Inombolo ye-EINECS: 1806241-263-5


Imininingwane Yomkhiqizo

Amathegi Omkhiqizo

Imininingwane Yomkhiqizo

Ibizo MicAFung
Inombolo ye-CAS 235114-32-6
Ifomula yamangqamuzana C56h71NNO23S
Isisindo molecular 1270.28
Inombolo ye-einec I-1806241-263-5

I-Clinical Pharmacology

Lo mkhiqizo ungowokufakwa kwe-intravenous. Ukuhlushwa kwe-plasma kufinyelela esilinganisweni ekugcineni kokufakwa, kanye nokuqedwa kwe-Half-Life amahora angama-13,9. Ukuhlushwa kweMicafungin esisekelweni, isibindi, izicubu zensizwa kanye nezinso kuphakeme kakhulu, kepha akutholakalanga ku-verebrospinal fluid. Ngemuva kokufakwa kwe-intravenous, kuhlanganiswe kakhulu esibindini futhi kufakwe ku-femeks nomchamo.

Sebenza

Umthamo onconyiwe wokwelashwa kwe-esophageal candidiasis ngu-150 mg ngosuku, kanye nethamo elinconyiwe lokutheleleka kokutheleleka kwe-candida ku-hematopoietic stem iziguli zokufakelwa kwamaseli ngosuku. Ngokusho kwemininingwane etholakalayo yomtholampilo, inkambo ephakathi yokwelashwa noma ukuvimbela lezi zifo ezimbili ezingenhla yizinsuku eziyi-15 nezinsuku eziyi-19, ngokulandelana. Umuthi ulungiselelwe futhi uvinjelwe ngosawoti ojwayelekile noma umjovo ongu-5% we-dextrose. Isikhathi sokuphatha kufanele okungenani sibe yihora eli-1, uma kungenjalo kulula ukukhiqiza ukusabela okungekuhle.

Ukusebenzisana Kwezokwelapha

Ukuqothuka kwe-Plasma ephakeme ye-nifedipine kungandiswa ngo-42%, futhi uma kunesidingo, cabanga ukunciphisa umthamo we-nifedipine noma uyeke umuthi. Le ndawo ngaphansi kwejika lokuhlushwa le-plasma lokulwa nokwenqatshwa kwezidakamizwa uSirolimus wenqatshwa ngo-21%, futhi ukuncishiswa kwethamo le-sirolimus kufanele kubhekwe njengokufanele. Izidakamizwa ze-Antifungal, i-Clinical Pharmacology, ukusetshenziswa, ukuphendula okuphikisayo, njll. IMicafungin

Umthandi

Yini amanani akho?

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Ungakwazi yini ukunikeza imibhalo efanele?

Yebo, singanikeza amadokhumenti amaningi kubandakanya nezitifiketi zokuhlaziywa / ukuvumelana; Umshuwalense; Imvelaphi, kanye neminye imibhalo yokuthumela lapho kudingeka khona.

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Ingabe uqinisekisa ukulethwa okuphephile nokuvikelekile kwemikhiqizo?

Yebo, sihlala sisebenzisa ukufakwa kwekhwalithi ephezulu yokuthumela ngaphandle. Siphinde futhi sisebenzise ukupakisha ngobuhle obukhethekile bezimpahla eziyingozi futhi siqinisekise ama-Stores Storaders abandayo ezinto zokushisa ezibucayi. Izidingo zokupakisha ezikhethekile nezidingo ezingezona ezijwayelekile zingathola imali eyengeziwe.


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