IGlucagon

I-Glucagon API

I-Glucagon iyi-hormone yemvelo ye-peptide esetshenziswa njengokwelashwa okuphuthumayo kwe-hypoglycemia enzima futhi yafundelwa indima yayo ekulawuleni i-metabolic, ukuncipha kwesisindo, kanye nokuxilongwa kokugaya ukudla.

Inqubo Nocwaningo:

I-glucagon ibophezela ku-glucagon receptor (GCGR) esibindini, ivuselele:

Ukwephulwa kwe-glycogen ukukhulisa ushukela wegazi

I-Lipolysis kanye nokuhlanganisa amandla

Ukuguqulwa kwe-gastrointestinal motility (okusetshenziswa ku-radiology)

Ibuye ihlolwe ekukhuluphaleni, uhlobo lwesifo sikashukela sohlobo 2, kanye nokwelashwa kwe-agonist okukabili/okuthathu nge-GLP-1 ne-GIP.

Izici ze-API (Gentolex Group):

I-peptide yokuhlanzeka okuphezulu (≥99%)

Ikhiqizwe nge-solid-phase peptide synthesis (SPPS)

Ikhwalithi efana ne-GMP

Ifanele imijovo kanye nezinsiza zezimo eziphuthumayo

I-Glucagon API ibalulekile ekusindiseni i-hypoglycemia, i-imaging yokuxilonga, kanye nocwaningo lwe-metabolic disorder.