I-Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH

I-Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH

I-Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH iyibhulokhi yokwakha esebenzayo ye-amino acid eklanyelwe ukulethwa kwezidakamizwa okuhlosiwe kanye ne-bioconjugation. Ifaka ingxenye ye-Eic (eicosanoid) yokusebenzisana kwe-lipid, i-γ-Glu yokukhomba, kanye nezikhala ze-AEEA zokuguquguquka.

 
Ucwaningo Nezicelo:

Isetshenziswa ku-prodrug synthesis, ukuthuthukiswa kwe-ADC, kanye nomklamo we-nanocarrier

Ithuthukisa ukuqondiswa kwe-membrane, ukunyibilika, nokusebenza kahle kokuhlanganisa

Ifanele i-SPPS ocwaningweni oluthuthukisiwe lwe-peptide–drug conjugate

Izici Zomkhiqizo (Gentolex Group):

I-Fmoc evikelwe, ukuhlanzeka okuphezulu (≥99%)

Iqukethe amaqembu e-OtBu ahlukanisekayo okuhlanganiswa okulawulwayo

I-Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH ilungele izinhlelo zokulethwa okunembayo kanye nomklamo osebenzayo we-peptide.