I-Elamipretide

Elamipretide API

I-Elamipretide iyi-tetrapeptide ehloselwe i-mitochondria eyenzelwe ukwelapha izifo ezibangelwa ukungasebenzi kahle kwe-mitochondrial, okuhlanganisa i-mitochondrial myopathy eyinhloko, i-Barth syndrome, nokuhluleka kwenhliziyo.

Inqubo Nocwaningo:
I-Elamipretide iqondise ngokukhethekile i-cardiolipin kulwelwesi lwangaphakathi lwe-mitochondrial, ithuthukisa:
I-Mitochondrial bioenergetics
Ukukhiqizwa kwe-ATP
Ukuphefumula kwamaselula nokusebenza kwesitho

Ibonise amandla okubuyisela ukwakheka kwe-mitochondrial, ukunciphisa ukucindezeleka kwe-oxidative, nokuthuthukisa ukusebenza kwemisipha nenhliziyo kuzo zombili izifundo zomtholampilo kanye nezandulela.