I-Triampenenene ye-Triampene ikakhulukazi ekwelapheni izifo ezimnandi
Imininingwane Yomkhiqizo
| Ibizo | Triampene |
| Inombolo ye-CAS | 396-01-01-0 |
| Ifomula yamangqamuzana | C12h11n7 |
| Isisindo molecular | 253.26 |
| Inombolo ye-einec | 206-904-3 |
| Iphuzu elibilayo | 386.46 ° C |
| Ubumsulwa | 98% |
| Ukubeka | Kuvalwe e-Dry, lokushisa legumbi |
| Isithunzi | Impushana |
| Umbala | Ophuzi ophuzi kuphuzi |
| Ukufaka ndawonye | Isikhwama se-Aluminium + Aluminium |
Amanyanjana
6-Phenyl-; 7-Pteridinetriamine, 6-Peteninet-4; I-Diulen; Ditak; Diureeth; DyrenUM; DYTAC
Umphumela wekhemisi
Ukucubungula
I-Triampetene iyi-diuretic ye-potassium-sparing-sparing, enomphumela we-diuretic wokugcina i-potassium kanye ne-excreting sodium efana ne-spirinonolactone, kepha indlela yokusebenza yehlukile. Kusenokutholwa kwe-diuretic ngemuva kokuvimbela imfihlo ye-aldosterone nge-sodium chloride noma ukususa indlala ye-adrenal. Indawo yayo yesenzo ise-tubule edidiyelwe distal, ivimbela ukushintshaniswa kwe-sodium ne-potassium ion, ukwandisa ukukhishwa kwe-NA + kanye no-Arcy. Kungavimba futhi nokuvuselela kabusha kwe-NA + ne-Secreion ye-K + nge-duct yokuqoqa. Umphumela we-diuretic walo mkhiqizo ubuthakathaka. Lapho isetshenziswa ngokuhlanganiswa nama-diuretics afana neThiazide, ayikwazi ukuqinisa umphumela we-natriuretic no-diuretic wokugcina, kepha futhi anciphise ukusabela okubangelwa okubangelwa ukukhishwa kwe-potassium kokugcina. Ngaphezu kwalokho, kukhona nomphumela we-excreting acid. Ukusetshenziswa kwesikhathi eside kungakhuphula amazinga e-Urea. Isetshenziselwa ikakhulukazi ama-edema noma ama-ascites angathinteki kahle, i-cirrhosis yesibindi nama-nephritis angapheli. Ingase futhi isetshenziselwe iziguli ezingasebenzi nge-hydrochlorothiazide noma i-spironolactone.
Umphumela wekhemisi
Lo mkhiqizo uyi-diuretic-sparing-sparing diuretic, evimbela ngokuqondile i-NA + -K + Exchange phakathi kwe-tubule ye-distal kanye nokuqoqa i-duct yezinso, ukukhulisa ukukhishwa kwe-NA +, CL-, namanzi, ngenkathi kunciphisa ukukhishwa kwe-K +.
Izinkomba
Isetshenziselwa ikakhulukazi ukwelashwa kwezifo ze-Edema; kufaka phakathi ukwehluleka kwenhliziyo okugcwele, ama-ascites wesibindi e-CIRRHOSS, i-Nephrotic Syndrome namanzi nokugcinwa kwe-sodium ngesikhathi sokwelashwa kwe-adrenal glucocorticoids; Ingasetshenziselwa futhi ukwelashwa kwe-idiopathic edema.
Umsebenzi
I-diuretic ebuthakathaka. Umphumela ushesha futhi uhlala isikhashana, i-divesis iqala amahora ama-2 ngemuva kokuphathwa ngomlomo, ifinyelela inani eliphakeme ngamahora ayi-6, futhi umphumela uthatha amahora angu-8 kuya kwayi-12. Isetshenziselwa ngokomzimba kwe-edema noma ama-ascites angabangelwa ukwehluleka kwenhliziyo, i-cirrhosis yesibindi nama-nephritis angapheli, futhi asetshenziselwa i-hydrochlorothiazide noma i-spironolactone. amacala. Lo mkhiqizo unomsebenzi wokuqeda i-uric acid futhi ulungele ukwelashwa kwe-gout.
