I-Reverse T3 ye-Protein synthesis, i-thermoregulation, ukukhiqizwa kwamandla kanye nomthethonqubo
Imininingwane Yomkhiqizo
| Ibizo | Buyisela emuva t3 |
| Inombolo ye-CAS | 5817-39-0 |
| Ifomula yamangqamuzana | C15h12I3NO4 |
| Isisindo molecular | I-650.97 |
| Iphuzu elincibilikayo | 234-238 ° C |
| Iphuzu elibilayo | 534.6 ± 50.0 ° C |
| Ubumsulwa | 98% |
| Ukubeka | Gcina endaweni emnyama, eboshwe esomile, esitolo efrijini, ngaphansi -20 ° C |
| Isithunzi | Impushana |
| Umbala | Pale beige to brown |
| Ukufaka ndawonye | Isikhwama se-Aluminium + Aluminium |
Amanyanjana
UReverset3 (3,3 ', 5'-TriioDo-L-Thictricnine); l-tyrosine, o- (4-hydroxy-3,5-diodophenyl) -3-iodo -; (2s) [4- (4-hydroxy-3,5-diodophenoxy) -3-iodophenyl] propanoicacid; reverset3; t3; liotyhronin; l-3,3; ntathu; -Isixazululo se-hermonine (reverset3) Solution
Umphumela wekhemisi
Ukufanisa
I-thyroid gland iyindlala enkulu kunazo zonke endocrine emzimbeni womuntu, kanye nezinto eziphambili ezisebenzayo ezifihliwe yiTetraiodothyronine (T4) ne-TriodoTothyronine (T3), ezibaluleke kakhulu kwi-Protein synthesis, ukukhiqizwa kwamazinga okushisa komzimba kanye nendima ye-Rectional nendima yomthetho. Iningi le-T3 ku-serum liguqulwa lisuka ekunikezelweni kwezifo zesifo se-peripheral, futhi ingxenye encane ye-T3 itholwe ngokuqondile yi-thyroid futhi ikhishwe egazini. Iningi le-T3 ku-serum liboshelwe amaprotheni abophayo, cishe ama-90% awo wonke ama-globulin (TBG) aboshelwe ama-albhamuin (i-TBG), bonke ababoshelwe ku-albhamuin, futhi inani elincane kakhulu liboshelwe kwi-»thyroxine-binding prealbumin (TBPA). Okuqukethwe kwe-T3 ku-serum kungu-1 / 80-1 / 50 walokho kwe-T4, kepha umsebenzi webhayoloji we-T3 unezikhathi ezi-5-10 ze-T4. I-T3 idlala indima ebalulekile ekwahluleleni isimo somzimba somzimba womuntu, ngakho-ke kubaluleke kakhulu ukuthola okuqukethwe kwe-T3 ku-serum.
Ukubaluleka Komtholampilo
Ukuzimisela kwe-triodoothyronine kungenye yezinkomba ezibucayi zokuxilongwa kwe-hyperthyroidism. Lapho i-hyperthyroidism inyuka, futhi iyisisekelo sokuphindaphinda kwe-hyperthyroidism. Ngaphezu kwalokho, kuzokwanda ngesikhathi sokukhulelwa kanye ne-hepatitis enamandla. I-Hypothyroidism, i-goiter elula, i-nephritis eyingozi nengamahlalakhona, i-hepatitis engapheli, i-cirrrhosis yesibindi yehlile. Ukuhlushwa kwe-serum t3 kukhombisa ukusebenza kwe-thyroid gland ezicutshini eziseduze kunokuba isimo sokumfihlo sendlala yegilo. Ukuzimisela kwe-T3 kungasetshenziselwa ukuxilongwa kwe-T3-Hyperthythroidism, ukukhonjwa kwe-hyperthyroidism yakuqala kanye nokuxilongwa kwe-pseudothothyrotosis. Izinga le-serum t3 eliphelele lihambisana noshintsho lwe-T4 level. Kuyinkomba ebucayi yokuxilongwa komsebenzi we-thyroid, ikakhulukazi ukutholakala kwangaphambi kwesikhathi. Kuyinkomba ethile yokuxilonga ye-T3 hyperthythroidism, kepha inenani elincane lokuxilongwa komsebenzi we-thyroid. Ezigulini eziphathwe ngemithi ye-thyroid, kufanele zihlanganiswe ne-thyroxine (TT4) futhi, uma kunesidingo, iThyroTropin (THS) ngasikhathi sinye ukusiza ukwahlulela isimo se-thyroid .roid)
