I-Semaglutide ayiyona nje isidakamizwa sokulahlekelwa isisindo-iyindlela yokwelapha ephumelelayo ehlose izimbangela zezinto eziphilayo zokukhuluphala.
1. Izenzo Ebuchosheni Ukucindezela Isifiso Sokudla
I-Semaglutide ilingisa i-hormone yemvelo ye-GLP-1, eyenza ama-receptors asebenze ku-hypothalamus-indawo yobuchopho ebhekene nokulawula ukulamba nokugcwala.
Imiphumela:
Khulisa ukusutha (uzizwa ugcwele)
Yehlisa indlala nokulangazelela ukudla
Yehlisa ukudla okuqhutshwa umvuzo (izifiso zikashukela nokudla okunama-calorie aphezulu)
✅ Umphumela: Ngokwemvelo udla amakhalori ambalwa ngaphandle kokuzizwa uncishwe okuthile.
2. Yehlisa Ukukhipha Isisu
I-Semaglutide inciphisa izinga lapho ukudla kushiya isisu futhi kungena emathunjini.
Imiphumela:
Yandisa umuzwa wokugcwala ngemva kokudla
Iqinisa izinga le-glucose ngemuva kokudla
Ivimbela ukudla ngokweqile kanye nokudla phakathi kokudla
✅ Umphumela: Umzimba wakho uhlala wanelisekile isikhathi eside, wehlisa ukudla okuphelele kwekhalori.
3. Ithuthukisa Ukulawulwa Koshukela Wegazi
I-Semaglutide ithuthukisa ukugcinwa kwe-insulin lapho ushukela wegazi uphakeme futhi inciphisa ukukhululwa kwe-glucagon, i-hormone eyandisa ushukela wegazi.
Imiphumela:
Ithuthukisa i-glucose metabolism
Yehlisa ukumelana ne-insulin (okunomthelela omkhulu ekugcineni amafutha)
Ivimbela ukukhuphuka nokwehla kukashukela egazini okuvusa indlala
✅ Umphumela: Indawo ye-metabolic ezinzile esekela ukushiswa kwamafutha esikhundleni sokugcina amafutha.
4. Ikhuthaza Ukulahleka Kwamafutha Futhi Ivikela IMisa Yemisipha Ethambile
Ngokungafani nezindlela zendabuko zokulahlekelwa isisindo ezingase zibangele ukulahlekelwa kwemisipha, i-Semaglutide isiza umzimba ukuba ushise amafutha ngokukhethayo.
Imiphumela:
Yandisa i-oxidation yamafutha (ukushiswa kwamafutha)
Yehlisa amafutha e-visceral (azungeze izitho), axhumene nesifo sikashukela nesifo senhliziyo
Igcina isisindo somzimba esithambile ukuze ukwakheka komzimba okunempilo
✅ Umphumela: Ukuncipha kwesikhathi eside kwamaphesenti amafutha omzimba kanye nempilo ye-metabolic ethuthukisiwe.
Ubufakazi Bomtholampilo
I-Semaglutide ibonise imiphumela engakaze ibonwe ezivivinyweni zomtholampilo:
| Isivivinyo | Umthamo | Ubude besikhathi | Ukuncipha Kwesisindo Okumaphakathi |
|---|---|---|---|
| ISINYATHELO 1 | 2.4 mg ngesonto | 68 amasonto | I-14.9% yesisindo somzimba wonke |
| ISINYATHELO 4 | 2.4 mg ngesonto | 48 amasonto | Ukulahlekelwa kwesisindo okuqhubekayo ngemva kwamasonto angu-20 okusetshenziswa |
| ISINYATHELO 8 | I-2.4 mg iqhathaniswa nezinye izidakamizwa ze-GLP-1 | Ikhanda ngekhanda | I-Semaglutide ikhiqize ukunciphisa okukhulu kwamafutha |
Isikhathi sokuthumela: Oct-23-2025