I-MECOBOBALAmin ingeyokwelashwa kokuphazamiseka kwezinzwa ze-peripheral

Umsebenzi we-physiological

I-Methylcobalamin iyisidakamizwa sokwelashwa kokuphazamiseka kwezinzwa ze-peripheral. Uma kuqhathaniswa namanye amalungiselelo we-Vitamin B12, anokutholwa okuhle kwezicubu zezinzwa. Kungakhuthaza i-metabolism ye-nucleic acid-lipid ukusabela kwe-methyl ukusabela nokulungisa izicubu zezinzwa ezilimele. Idlala indima ye-Coenzyme yenqubo yokuhlanganisa i-methoineine kusuka ku-homocysteine, ikakhulukazi ibamba iqhaza ekuhlolweni kwe-thymidine kusuka ku-deoxyurine nucleoside, futhi ikhuthaza ukuhlanganiswa kwe-DNA ne-RNA. Ngaphezu kwalokho, ekuhlolweni kwamaseli akhazimulayo, umuthi wandisa umsebenzi wokuhlangana we-methionionine futhi ukhuthaza ukuhlanganiswa kwe-imetiyini lipid lecithin. Ukwenza ngcono ukuphazamiseka kwe-metabolic yezicubu zezinzwa kungakhuthaza ukuhlanganiswa kwama-aonjons namaprotheni abo, kwenze ijubane lezokuthutha lamaprotheni amathambo asondele kokujwayelekile, futhi agcine umsebenzi wama-aetons. Umjovo we-methylcobalamin ungavimba futhi ukufakwa kwezicubu zezinzwa ezingajwayelekile, ukukhuthaza ukuvuthwa nokuhlukaniswa kwe-erythroblasts, futhi kuthuthukise i-anemia. I-methylcobalamin ingabuyisela ngokushesha ukubalwa kweseli okubomvu kwegazi, i-hemoglobin, nenani le-hematocrit lamagundane ancishisiwe ngenxa yokushoda kwe-B12. Kusetshenziswe eMegaloblastic Anemia kanye nokuphazamiseka kwe-peripheral nerve okubangelwa ukuntuleka kwe-Vitamin B12.

Umphumela wekhemisi

I-methylcobalamin iyisisulu sevithamini B12. Ibizwa ngegama lesakhiwo salo samakhemikhali. Kufanele ibizwe nge- "methyl vitamin B12". Kungakhuthaza i-metabolism yamafutha, kuvuse ukuhlanganiswa kwe-lecithin kumaseli we-schwann, ukulungisa i-welmelin sheath elonakalisiwe, futhi kuthuthukise ukuvezwa kwe-nerve conduction; ingangena ngokuqondile amaseli ezinzwa futhi ivuselele ukuvuselelwa kabusha kwama-axons alimele; vuselela ukwakheka kwamaprotheni amangqamuzana ezinzwa, qinisa ama-axon anwabolism, vimbela ukonakala kwe-axon; Bamba iqhaza ku-nucleic acid synthesis, ukhuthaze umsebenzi we-hematopopoitic. Ngokwengqondo, kuvame ukusetshenziselwa ukwelashwa kwe-neuropathy sikashukela, futhi ukusetshenziswa kwayo kwesikhathi eside nakho kunomthelela othile ezinkingeni zemithambo yegazi emikhulu esifowe sikashukela. I-Methylcobalamin isetshenziselwa ikakhulukazi izifo ezihlaselayo zezinzwa ezibangelwa isifo sikashukela kanye ne-megaloblastic anemia ebangelwa ukuntuleka kwe-Vitamin B12. Isetshenziswa kabanzi ngomtholampilo ngemiphumela emibi embalwa.

Umsebenzi
Kusetshenziselwa ukwelapha izifo zohlelo lwezinzwa, kudambisa ubuhlungu kanye nokuzindla, ngokushesha kothambisa ubuhlungu be-neulthia, uthuthukise izinhlungu ezibangelwa yi-Cervical Spondylosis, bese uphatha izithulu ezingazelelwe, njll.