I-Glepaglutide

I-Glepaglutide API

I-Glepaglutide iyi-analog esebenza isikhathi eside ye-GLP-2 eyenzelwe ukwelapha i-short bowel syndrome (SBS). Ithuthukisa ukumuncwa nokukhula kwamathumbu, kusize iziguli zehlise ukuncika ekondlekeni kwabazali.

Inqubo Nocwaningo:

I-Glepaglutide ibophezela ku-glucagon-like peptide-2 receptor (GLP-2R) emathunjini, ikhuthaze:
Ukukhula kwe-mucosal nokuvuselelwa
Ukumuncwa okuthuthukisiwe komsoco noketshezi
Ukunciphisa ukuvuvukala kwamathumbu

Ucwaningo lwezokwelapha lubonise ukuthi i-Glepaglutide ingakhuphula ukusebenza kwamathumbu futhi ithuthukise izinga lokuphila ezigulini ze-SBS.

Izici ze-API (Gentolex Group):

I-analog ye-peptide esebenza isikhathi eside
Ikhiqizwe nge-solid-phase peptide synthesis (SPPS)
Ukuhlanzeka okuphezulu (≥99%), ikhwalithi efana ne-GMP

I-Glepaglutide API iyindlela yokwelapha ethembisayo yokwehluleka kwamathumbu nokuvuselelwa kwamathumbu.